Ramadan Fasting and Liver Diseases#

 our new article titled: 

Ramadan Fasting and Liver Diseases: A review with practice advices and recommendations

Mohamed H Emara 1, Hanan H Soliman 2, Mohamed Elnadry 3, Ebada Mohamed Said 4, Sherief Abd-Elsalam 2, Hassan E Elbatae 1, Tarik I Zaher 5, Shamardan Ezzeldin S Bazeed 6, Ahmed Abdel-Razik 7, Salem Youssef Mohamed 8, Asem Elfert 2, “Egyptian Ramadan Fasting, Liver Diseases Interest Group”
Affiliations
  • 1Department of Hepatology, Gastroenterology and infectious diseases, Faculty of Medicine, Kafrelsheikh University, Kafr El-Shikh, Egypt.
  • 2Tropical medicine and infectious diseases Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
  • 3Hepato-gastroenterology and infectious diseases Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
  • 4Gastroenterology and Infectious Diseases Department, Faculty of Medicine, Benha University, Benha, Egypt.
  • 5Department of Tropical Medicine, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
  • 6Tropical Medicine and Gastroenterology Department, Faculty of Medicine, South Valley University, Qena, Egypt.
  • 7Department of Tropical Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
  • 8Department of Internal Medicine, Faculty of Medicine, Zagazig University, Zagazig, Egypt.


  • PMID: 33369880
    •  
  • DOI: 10.1111/liv.14775.

  • Abstract

    Ramadan fasting is obligatory for Muslim healthy adults. However, there are many exemptions from fasting; including patients, whose diseases will be aggravated by fasting. Muslim patients with different liver diseases are frequently seen in the clinics discussing their intent to fast this month with their treating physicians. To answer our patients' inquiries about the expected benefits and/or risks of fasting and delivering them the best care, we carried out this review and we draw advices and recommendations based on the available evidence. A web-based search, combining multiple keywords representing different liver diseases with Ramadan fasting had been carried out. To answer the research question: Do adult Muslim patients with different liver diseases who fast the month of Ramadan have had a deleterious effect on their health in comparison to those who did not fast? Relevant publications were retrieved. No randomized controlled trials were focusing on Ramadan fasting and liver diseases in the filtered databases e.g. Cochrane library. Consequently, non-filtered databases e.g. PubMed, Google Scholar, and Egyptian Knowledge Bank searched and full-text high-quality research articles were carefully analyzed to draw recommendations. Other relevant publications with low quality of evidence like case studies and short communications were also reviewed to address practice advices. Although Ramadan fasting was found beneficial for patients with NAFLD, it was found deleterious to patients with Child B and C cirrhosis and patients with peptic ulcer. Patients with chronic hepatitis, Child A cirrhosis, and those with non-complicated liver transplant can fast with pre-fasting assessment and strictly follow up.

    Keywords: Cirrhosis; Liver diseases; NAFLD; Ramadan fasting; Recommendations; Variceal bleeding.

  • . 2020 Dec 28.

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