Difficult To Treat Recurrent Esophageal Dysphagia Due To Secondary Esophageal Motility Disorders: A 24 Weeks Follow Up: Case Report

The third article published by our journal (African journal of gastroenterology and hepatology. ajgh.net): http://www.ajgh.net/Volumes/word%20document.docx
Abstract

Limited data are available on the prevalence of esophageal motility disorders (OMD) with a suggested range of 4-12% in cases with dysphagia. The proposed pathophysiology is either impairment of inhibitory innervation or overactivity of excitatory innervation. The optimal treatment is not defined until now. This case represented one of the secondary OMD in a 70 years year diabetic patient with ischemic cardiomyopathy, who was complaining of recurrent daily intermittent dysphagia to solids and fluids, with a previous vague history of esophageal dilatation without available documentation. After endoscopy with multiple biopsies and barium imaging, the picture of the corkscrew esophagus was revealed. The patient, who was already on nitrates, failed to respond to twice daily proton pump inhibitor for two months with a prokinetic drug, calcium channel blocker, and the first session of endoscopic esophageal dilatation. After the second session of dilatation, we add sodium alginate with the substitution of nitrates with sildenafil, and the patient reported a gradual improvement of dysphagia especially to fluids with decreasing in daily attacks. We learn from this case that there is a different patient to patient response, which necessitates the use of different treatment modalities even just switching between nitric oxide scavengers for each patient.

Keywords: Case Report; Dysphagia; esophageal Motility Disorders.