A 22-year-old woman presented with #bleeding per rectum, bloody diarrhea, and severe anemia. The patient gives a history of ulcerative colitis—the patient is on treatment for #ulcerative-colitis in the form of #Pentasa, #corticosteroids, and other #conservative treatments. She underwent a #colonoscopy. The scope revealed severe colitis with multiple pseudopolyps and whitish-sloughed mucosa. The extent of the inflammation is about 2/3 of the colon extending from the rectum. Multiple biopsies were taken for histopathology.
The patient and her relatives ask about biological therapy; what is your opinion?
How to confirm or exclude associated #GI infections?
How to exclude intestinal #dysplasia?
What is the #follow-up plan for this patient?
Is it essential to check for #primary non-response to #TNFα antagonists?
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